Since the product is sterile and usually does not contain antibiotics, aseptic procedures must be followed at all times. Whenever possible use a certified biological safety cabinet.

Granules, flocculent material or turbidity may develop after thawing. This particulate matter does not alter the performance of the serum as a supplement for cell culture medium. Repeated freezing/thawing of serum may increase the amount of precipitate and is therefore not recommended. If you do not intend to use an entire bottle of serum within 2 freeze/thaw cycles, aliquot it into usable quantities in sterile containers before freezing a second time.

Wipe the outside of each bottle with a disinfectant solution, proven effective against the normal bioburden in your laboratory, before setting it on the work surface. Remove the heat seal and wipe the cap with the disinfectant solution.

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